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CRYSTALLINIC ACID
Descriptors Found:
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DeCS
Descriptor
English
:
Novobiocin
Descriptor
Spanish
:
novobiocina
Descriptor
Portuguese
:
Novobiocina
Synonyms
English
:
Calcium, Novobiocin
Crystallinic Acid
Monosodium Salt Novobiocin
Novobiocin Calcium
Novobiocin Sodium
Novobiocin, Monosodium Salt
Sodium, Novobiocin
Streptonivicin
Tree Number:
D03.383.663.283.446.139.500
D03.633.100.150.446.139.500
D09.408.554
Definition
English
:
An antibiotic compound derived from
Streptomyces
niveus. It has a chemical structure
similar
to coumarin.
Novobiocin
binds to
DNA gyrase
, and blocks
adenosine
triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra
Pharmacopoeia
, 30th ed, p189)
Pharmacological Action:
Anti-Bacterial Agents
Enzyme Inhibitors
Nucleic Acid Synthesis Inhibitors
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
28212
Unique Identifier:
D009675
Occurrence in VHL
:
Similar:
DeCS